Registration
Description
Genomic instability is an invariant property of cancer cells that is characterized with an increased rate of mutations and gross chromosome rearrangements. Spontaneous DNA damage is detected very early in the cancer process, as a consequence of oncogene-induced replication stress. Recent evidence indicate that replication stress, and more generally DNA Damages, promote the release of DNA fragments that accumulate in the cytosol and activates the cGAS-STING pathway, the expression of interferon genes and the inflammatory response. Since both radiation- and chemo-therapy frequently target DNA and DNA replication, DNA damage-induced cytokines secretions and inflammatory response should have strong implications in cancer therapy. We wish to bring together cancer biologists, immunologists and basic research scientists in the field of DNA Damage Response, to foster interactions and scientific discussions.
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The participation to the meeting is free but the registration is mandatory.
A poster session will be organized but the number is limited to 40.
A selection will be made if necessary.
If you choose to present a poster, please provide in a single word file to upload at the time of your registration:
- Title
- Author list
- Address
- Abstract (250 words max)
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Event
DINGO "DNA Damage Response Innate Immunity & Inflammation"
75005 Paris
FRANCE
Organizer contact
DINGO 2018